Clara Marlowe - Dr Pua - Week 7

 On Monday, I watched a uterine fibroid embolization. The patient had 3 fibroids that needed to be blocked from receiving blood flow without blocking blood flow to the ovaries as the patient still wanted to maybe become pregnant. The anatomy was very difficult to navigate because the vasculature becomes tangled and coiled near the fibroids, so this procedure took a long time just to guide the wire into the correct vessel. 

On Tuesday, I watched a pulse electric field ablation which is what my research project is based on. The needle sends electric field pulses into the lesion, causing pores to form in the cell membrane and the cytoplasm, proteins, and other innards begin leaking out. Combined with immunotherapy, this procedure can result in a non targeted effect where lesions that were not directed ablated are also attacked by the immune system. The dying cancer cells release antigens which result in a specific immune response. However, this response is only observed in 20% of patients and is not well predicted. 

Thursday, I watched more ablations with Dr. Mcclure. Friday, I watched a lung biopsy with Dr. Pua and went to clinic with Dr. Pua. 

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