Anna Hazelwood - Dr. Evelyn Horn - Week 7

This week I was able to get access to Epic in order to access patient health information for the whole genome study. Using the data I merged last week, I was able to copy over MRI results for patients with MYBPC3 mutations in order to combine the results and look for trends in both the structural and functional results. I was then able to combine these results into my presentation about my research on Tuesday.

I was also able to see an open heart surgery with Dr. Goldberg, a cardiothoracic surgeon. This surgery was an aortic aneurism repair and involved placing the patient on bypass, removing the aortic arch and the major vessels extending outwards, and then sewing in a graft into the missing places. After each aspect of the graft was attached, the blood flow was restored to that section and Dr. Goldberg searched for leaks. Once all of the sections were attached, blood flow was restored to the heart and chest tubes were inserted to monitor air and fluid buildup in the chest area post operation. Tyler and I attended the surgery for 6 hours, but the preparations were taking place before we arrived and after we left. I learned that there are many things that have to be adjusted during the procedure such as the blood pressure. This is adjusted by the anesthesiologists using medications to ensure that when the surgeons are pressing on parts of the heart and the aorta that there are no complications. Also, when the patient is put on the bypass machine, tubes are attached to the body to take the blood out, pass it through the oxygenation machine, and then put it back into the body. This entire time, the body is being cooled via ice packs around the patient's head and the blood is cooled before it re-enters the body to restrict blood flow. They are also able to monitor blood flow to the patient's brain via infrared sensors on their forehead. 




(photo from Newport Cardiac and Thoracic Surgery)
(photo from Getinge.com)

Above shows the relative portions of the aorta that were replaced with a graft, and what the graft material looks like.

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